PET/CT Predicts Survival After Chemoimmunotherapy for Primary Mediastinal Large B-Cell Lymphoma - Assessment of the role of PET/CT after rituximab and anthracycline-containing chemoimmunotherapy in patients with primary mediastinal large B-cell lymphoma.
Previous Updates:
  Prognostic Value of Pretreatment PET/CT in Patients With Head and Neck Squamous Cell Carcinoma - Determination of whether pretreatment quantitative and visual parameters seen on PET/CT using 18F-FDG add prognostic information for clinical staging in patients with head and neck cancer, as published in the April 2014 issue of the American Journal of Roentgenology.
  Preoperative PET and the Reduction of Unnecessary Surgery Among Newly Diagnosed Lung Cancer Patients - Examination of the real-world effectiveness of PET in avoiding unnecessary surgery for newly diagnosed patients with non–small cell lung cancer.
  PET/CT in Head and Neck Squamous Cell Carcinoma with Negative Neck Palpation Findings - A prospective study to assess the clinical usefulness of PET/CT and MRI/CT imaging in detecting occult neck metastasis in patients with head and neck squamous cell carcinoma and negative neck palpation findings.
  PET/CT and Biomarkers for Early Treatment Response Evaluation in Metastatic Colon Cancer - Prospective evaluation of serial PET/CT imaging and measurements of tissue inhibitor of metalloproteinases-1 (TIMP-1), carcinoembryonic antigen (CEA), and liberated domain I of urokinase plasminogen activator receptor (uPAR(I)) for early assessment of treatment response in mCC patients. The Oncologist, January 2014.
  FDG-PET-CT is effective in selecting patients with poor long term survivals for colorectal liver met - Utilizing PET-CT as part of the staging process for colorectal liver metastases since 2008, we evaluated the survival outcomes of all patients managed by our specialist multi-disciplinary team.
  Breast Cancer Neoadj Treatment Monitoring with PET - Each anti-HER2 therapy was given alone for 6 wk, followed by 12 wk of the same therapy plus weekly paclitaxel. The early metabolic effects of the anti-HER2 therapies on the primary tumors and their predictive values for pathological complete response were assessed in a subset of patients with PET imaging.
  PET/CT for Operable Triple Negative Breast Cancer - The significance of FDG-PET/CT for speculating the malignant level and prognostic value of operable breast cancers, as published in the October 2013 issue of The Breast.
  Nasal T-cell Lymphoma Staging - The role of PET/CT for determining cancer staging by comparing its results to those of conventional staging methods in patients with nasal-type NK/T-cell lymphoma.
  Small Cell Lung Cancer Staging - Impact of PET Staging in Limited-Stage Small-Cell Lung Cancer in patients treated definitively with concurrent chemoradiation. From June 2013 issue of the Journal of Thoracic Oncology.
  Bone Marrow Involvement of Large B-Cell Lymphoma - In Newly Diagnosed Diffuse Large B-Cell Lymphoma, Determination of Bone Marrow Involvement with 18F-FDG PET/CT Provides Better Diagnostic Performance and Prognostic Stratification Than Does Biopsy, as reported in May 15, 2013 online issue of the Journal of Nuclear Medicine.
  Sarcoma Recurrence - The diagnostic accuracy and incremental value of integrated PET/CT vs CT alone in patients with a history of bone and soft tissue sarcoma, and who have clinically suspected disease recurrence.
  Cervical Cancer Treatment Monitoring - Changes in Cervical Cancer FDG Uptake During Chemoradiation and Association With Response - assessment of the changes in SUVmax, MTV, and FDGhetero during concurrent chemoradiation for cervical cancer and their association with post-treatment response. Published in the January 2013 issue of International Journal of Radiation Oncology, Biology, Physics.
  Breast Cancer Staging with PET/CT vs Conventional Imaging - Prospective investigation of the impact of FDG PET/CT at initial staging in a clinical setting, and comparison to the performance of conventional distant work-up, in patients with locally advanced breast cancer.
  Mid-Cycle Treatment Assessment of Follicular Lymphoma with PET - The investigators evaluated the prognostic value of PET performed during treatment and at the end of treatment in 121 patients with Follicular Lymphoma treated with first-line immunochemotherapy.
  Hodgkins Lymphoma Staging with PET/CT and Bone Marrow Biopsy - For patients with treatment-naive Hodgkin's lymphoma staged using PET/CT, routine bone marrow biopsy has little or no therapeutic consequence, according to research published online Nov. 13 in the Journal of Clinical Oncology.
  Gastric Cancer Staging with PET/CT - Assessment of the value of preoperative PET/CT in addition to routine CT, endoscopic ultrsound, and laparoscopic staging of localized gastric cancer. Orig published online in Cancer, 5/1/2012, by researchers at Memorial Sloan-Kettering Cancer Center.
  Lung Cancer - PET vs Conventional Imaging - The incremental management impact and prognostic value of staging with PET/CT in patients with non–small cell lung cancer being considered for potentially curative therapies. Correct stage, patient management, and overall survival was strongly predicted by PET/CT-directed choice of therapy.
  Salivary Duct Carcinoma - Diagnosis and Staging Using PET - Evaluation of the utility of 18F-FDG PET in preoperative staging, determining the extent of neck node involvement, and surgical planning for patients with salivary duct carcinoma of the major salivary gland.
  PRECIST vs RECIST in Assessing Neoadjuvant Tx for Esophageal Cancer - PET response criteria in solid tumors (PRECIST) was found to be more reliable than RECIST, and the strongest independent predictor of outcomes when evaluating chemotherapeutic response to esophageal cancer, according to researchers at Osaka University School of Medicine, as published in the June issue of The Journal of Nuclear Medicine.
  More Bone Lesions Detected by PET Bone Scan - NaF PET finds more breast cancer bone metastases than FDG PET, especially in cases of restaging, according to a Johns Hopkins study presented this week at the Society of Nuclear Medicine annual meeting.
  Lymphoma - PET and Involved Field Radiotherapy for Relapse - 83 patients with chemosensitive relapsed or primary refractory diffuse large B-cell lymphoma (DLBCL) underwent FDG-PET scans following second-line chemotherapy before high-dose therapy with autologous stem cell rescue(HDT/ASCR). We evaluated the prognostic value of having a negative FDG-PET scan before HDT/ASCR and whether IFRT improved the outcomes.
  Melanoma Treatment Monitoring - Imaging with [18F]fluorodeoxyglucose (FDG) –positron emission tomography (PET) allows early recognition of a response to agents that target key driver mutations in human cancer. We aimed to determine the metabolic response rate to vemurafenib in patients with advanced BRAF-mutant melanoma.
  Melanom Pre-Op Staging with PET - In patients with surgically treatable metastatic melanoma, FDG PET/CT can detect unexpected metastases that are missed or not imaged with conventional imaging, and can be considered as part of preoperative workup, according to a study in the April issue of the American Journal of Roentgenology.
  MRI for knee pain changes diagnosis, management - Knee MRI scans often change clinical diagnosis and patient management -- especially when patients present with lateral joint line pain and/or tenderness -- according to research presented earlier this month at the American Academy of Orthopaedic Surgeons meeting.
  PET After Radiation Therapy Predicts Lung Cancer Survival - MD Anderson Cancer Center researchers found that PET can provide strong indicators of overall and disease-free survival among patients with locally advanced non-small cell lung cancer (NSCLC) receiving radiation therapy, according to a study published in the February 2012 Journal of Nuclear Medicine.
  Triple-Negative Breast Cancer: Early Assessment with PET/CT During Neoadjuvant Chemotherapy - PET/CT identifies patients who are unlikely to achieve a pathologic complete response and who are at a high risk of early relapse. David Groheux, et al, Department of Nuclear Medicine, Saint-Louis Hospital, B2T, Doctoral School, IUH, University of Paris VII, Paris, France, J Nuclear Medicine, February 1, 2012, jnumed.111.094045.
  Interim FDG PET Scan in Diffuse Large B-Cell Lymphoma Treated With Anthracycline-Based Chemotherapy - Retrospective investigation of the prognostic value of PET performed in patients with DLBCL receiving chemotherapy plus rituximab. Images were interpreted both visually and by computing maximum standardized uptake value (SUVmax) between PET performed at baseline and after two cycles of chemotherapy. Violaine Safar, et al, Journal of Clinical Oncology, January 10, 2012 vol. 30 no. 2, 184-190.
  Contrast CT, PET/CT Assess Cancer Therapy for Melanoma - Immune-modulated and anti-angiogenic cancer therapeutics may not cause tumor shrinkage by conventional radiographic response. FDG-PET/CT and CT perfusion imaging were used to evaluate response to therapy. FDG-PET/CT and CT perfusion imaging were performed in a phase I trial of bevacizumab plus ipilimumab in patients (pts) with unresectable stage III or IV melanoma. Pamela DePiro, MD, et al, SSC09-08, Monday, Nov 28, 2011, Radiologic Society of North America, Chicago, IL.
  FDG PET in the Evaluation of Dementia - Review - Effectiveness and Safety of 18FDG PET in the Evaluation of Dementia: A Review of the Recent Literature - PET/CT scans used to evaluate pathophysiological changes in the brain holds great promise for diagnostic assessment of patients with Alzheimer’s Disease and other dementias. A review of recent literature demonstrates improved diagnostic accuracy of PET imaging compared to earlier data. Nicolaas Bohnen, MD, et al, Journal of Nuclear Medicine, pp.59-71, January 2012.
  MRI - Post Op Knee - MRI rules supreme in postoperative knee, but challenges remain - Ralph Gnannt, MD, Oral Presentation, RSNA Meeting, Chicago, IL, Nov. 2011.
  PET/CT prevents dissections for head and neck cancer patients - PET/CT scans to evaluate the response of patients who received chemoradiotherapy for head and neck cancer can prevent unnecessary dissections for some, researchers from the U.K. and the U.S. said at a Radiologic Society of North America (RSNA) 2011 scientific session. Wider use of this examination might prevent neck dissections that would ultimately prove to be unnecessary once pathological evaluations are completed. Manil Subesinghe, MD, Oral Presentation, RSNA Meeting, Chicago, Nov. 27, 2011.
  PET/CT assesses early chemo response in breast cancer - PET/CT's ability to evaluate pathological response after two cycles of neoadjuvant chemotherapy could help breast cancer patients avoid ineffective treatment.
  Rotator Cuff Recurrent Tear - MRI and Ultrasound imaging utilized for post surgical recurrent tears provide assessment of long term implications and outcomes.
  Survival and Outcomes of Post-treated Cervical Can - Investigation of relapse and survival outcomes in patients with cervical cancer, treated with curative intent chemoradiotherapy, and evaluated with a post‐therapy PET/CT scan. Cancer, Volume 117, Issue 17, September 1, 2011.
  ASCO: PET/CT helps predict metastatic breast cance - Utilizing maximum standardized uptake, and other values, on PET/CT scans can help predict prognosis in breast cancer patients with bone metastases. American Society of Clinical Oncology Breast Cancer Symposium, AuntMinnie, Sep 2011.
  Follicular Lymphoma - Prognostic Value of PET/CT - PET/CT utilized after induction immunochemotherapy. Assessment of Tx response and outcome accurately identified by PET/CT. JCO, Aug 2011.